<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=us-ascii"><meta name=Generator content="Microsoft Word 15 (filtered medium)"><style><!--
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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple style='word-wrap:break-word'><div class=WordSection1><div><p class=MsoNormal style='background:white'><span style='color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal style='background:white'><b><span style='font-size:14.0pt;color:black'>ENV H 405 Toxics and Human Health</span></b><span style='color:black'><o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'><a href="https://sdb.admin.uw.edu/timeschd/uwnetid/sln.asp?QTRYR=SPR+2023&SLN=14311">https://sdb.admin.uw.edu/timeschd/uwnetid/sln.asp?QTRYR=SPR+2023&SLN=14311</a><o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>Prerequisite: a minimum grade of 2.0 in BIOL 220; and a minimum grade of 2.0 in either CHEM 220, CHEM 224, CHEM 238, or CHEM 336.<o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal style='background:white'><b><span style='color:black'>COURSE DESCRIPTION </span></b><span style='color:black'><o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>This course will survey the most important concepts in toxicology, with a focus on the impact of chemicals on human and environmental health. Topics include principles underlying dose-response relationships, absorption, distribution, metabolism and elimination, followed by lectures on specific topics, including damage to major organs, cancer, birth defects, occupational hazards, and risk assessment and government regulation of environmental contaminants. <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal style='background:white'><b><span style='color:black'>COURSE LEARNING OBJECTIVES</span></b><span style='color:black'> <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>After completing this course, students should be able to: <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>Understand the basics of toxicant absorption, distribution, metabolism and excretion. <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>Gain an appreciation for how environmental toxicants interact with cellular pathways leading to the development of disease. <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>Become comfortable critically evaluating, discussing, and presenting current events relevant to the field of toxicology. <o:p></o:p></span></p></div><div><p class=MsoNormal style='background:white'><span style='color:black'>Reflect on the relevance of the field of toxicology to you as a scientist and as a proactive member of society<o:p></o:p></span></p></div><div><div><p class=MsoNormal><span style='color:black'><o:p> </o:p></span></p></div><div id=Signature><div><p class=MsoNormal style='background:white'><span style='font-size:12.0pt;font-family:"Arial",sans-serif;color:#222222'><a href="https://sdb.admin.uw.edu/timeschd/uwnetid/sln.asp?QTRYR=SPR+2023&SLN=14311"><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'>https://sdb.admin.uw.edu/timeschd/uwnetid/sln.asp?QTRYR=SPR+2023&SLN=14311</span></a><o:p></o:p></span></p></div></div></div></div></body></html>