[Biostudent] Undergrad Research - Koelle Lab

Biology Advising bioladv at uw.edu
Mon Nov 14 13:34:03 PST 2022


*Student Researcher Immunology/Virology lab*



T cells represent a critical component in immune protection from infectious
agents such as viruses and bacteria. The Koelle lab, in the Department of
Medicine, specializes in uncovering the unique targets and functional
characteristics of pathogen-specific T cells. They currently study T cells
in the context of SARS-CoV-2 (COVID-19), human herpesviruses (e.g. genital
and oral herpes, chickenpox, shingles), Merkel cell polyomavirus (a skin
oncovirus), Treponema pallidum (Syphilis), and Chlamydia trachomatis, and
support Clinical Trials that evaluate vaccines.



The Koelle lab is seeking a motivated and careful undergraduate for a
Student Researcher position. Genuine interest and curiosity about
microbiology and immunology, or bioinformatic processing of “big data”, is
important, regardless of the student’s career goals. Preference is given
for a late Sophomore to Junior who has some time left expected at UW so
they can learn the ropes and progress. Appropriate training in lab
techniques and safety requirement will be given. Must be up to date on
hepatitis B vaccination prior to working with human samples.



The student researcher would learn and assist with immunological assays,
molecular biology, and other general tasks. The core duties include
performing ELISA assays to measure cytokine levels. Other duties could
include preparing DNA from blood specimens, maintaining computer logs, and
assisting with routine molecular biology tasks such as molecular cloning,
plasmid DNA extraction, DNA sequencing and, as skills progress, cell
culture and cell-based assays. Commitment would be 10-20 hours a week.



Desired skills and characteristics include a) a real interest in biological
sciences and/or medicine, specifically vaccines, microbiology, immunology,
and infectious diseases, b) some experience with hands-on lab coursework,
c) an aptitude with math including large and small numbers/exponential
notation (there will be a four-operation BASIC math quiz at the interview),
d) familiarity with Excel and Windows/Mac OS and file structures, e)
hand-eye coordination and ability to use a binocular microscope, f) great
interpersonal and communication skills including voice, text, and email and
a commitment to staying in touch. Experience in computer programming in R
or Python is a plus.



We offer flexibility in the type of position: 499 student, paid, or
volunteer. For a paid position, there would be an expectation of higher
volume, more routine work tasks and sticking to a schedule with defined
hours. Interested students can progress to undergrad research “499”
projects around their senior year after they get familiar with the in-lab
science. Student helpers are welcome to join lab meetings (usually Monday
AM) if their schedule allows. The lab is based in the Center for Emerging
and Re-Emerging Infectious Diseases, close to UW Microbiology and
Immunology Depts at the UW SLU Campus (750 Republican Street). A shuttle
service runs to the main UW Campus and the downtown transit centers are
close by.



For more information regarding the lab’s areas of work see:

https://pubmed-ncbi-nlm-nih-gov.offcampus.lib.washington.edu/?term=koelle+dm

or

https://aid.uw.edu/people/faculty/infectious-diseases/david-Koelle



*Interested applicants, please contact Kerry Laing, PhD email:
laingk at uw.edu <laingk at uw.edu>*





David Koelle MD (he/him)

Professor, Division of Allergy and Infectious Diseases

Department of Medicine

University of Washington

--
*Biology Advising *
University of Washington, *BOX* 355320
318 Hitchcock Hall
http://www.biology.washington.edu/programs/undergraduate

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